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Message from Director

Welcome to the website for the Clinical Trials Statistical and Data Management Center (CTSDMC). We are associated with the Department of Biostatistics in the College of Public Health at the University of Iowa. If you have a need for a data management center, I encourage you to take some time to look around our website and become familiar with the many services that we offer. If you have any questions or would like any additional information, please contact us at 319-384-2832.



The CTSDMC was created in 1989 to provide statistical and data management support for multicenter clinical trials. We are associated with the Department of Biostatistics in the College of Public Health at the University of Iowa. The CTSDMC has a demonstrated history of assisting in the development and implementation of 12 large multicenter trials and two large epidemiological studies, at the University of Iowa and more than 80 other academic institutions. In each of our projects, the CTSDMC has provided leadership in study design, data management, project management, and statistical analysis. We offer an experienced and professional research and support team with a proven record and well-developed strategies for supporting the development, implementation, and completion of multicenter clinical trials and the mechanistic studies associated with those trials.

Mission Statement

The principal mission of the CTSDMC is to provide comprehensive, premier-quality data management, statistical analysis, and administrative support services to our clients through our commitment to accuracy, efficiency, and excellence in research.

The CTSDMC serves a broader mission to the academic and scientific communities by contributing new scientific knowledge and providing academic training in the development of state-of-the-art statistical methods.

Recent News

December 6, 2014

Meeting on Parkinson's Disease and Exercise

Several researchers from the College of Public Health (CPH), including CTSDMC Director Chris Coffey and Associate Director Dixie Ecklund, attended a meeting in Chicago that focused on exercise and Parkinson's disease. The CTSDMC has maintained a partnership with the Michael J. Fox Foundation, serving as the statistics core to multiple projects, including the Parkinson's Progression Markers Initiative (PPMI). The full CPH write-up can be found here.

October 28, 2014

CTSDMC 25th Anniversary Celebration

The Clinical Trials Statistican and Data Management Center celebrated its 25th Anniversary on October 28, 2014. Highlights included a visit from the Center's first director, Robert "Skip" Woolson; the dedication of the CTSDMC conference suite to honor William R. Clarke, CTSDMC director from 2000-2010; and the dedication of the Graduate Student Assistant Award in the Department of Biostatistics to Dr. Clarke for his 50+ years. The full write-up is available here. We thank the many former employees and colalborators who attended.

July 26, 2014

Fourth NeuroNEXT Study Receives Funding

The National Institute of Neorological Disorders and Stroke (NINDS) within the National Institutes of Health, has funded a fourth study in the Network for Excellence in Neuroscience Clinical Trials (NeuroNEXT). Patrick Lyden, chair of the Department of Neurology at Cedars-Sinai Medical Center, will lead the project "ZZ-3K3A-201: Safety evaluation of 3K3A-APC in ischemic stroke." The study aims to determine the safety, tolerability and activity of 3K3A-APC following the use of tissue plasminogen activator (tPA) in subjects who have experienced moderately severe actute hemispheric ischemic stroke. More information about this study (NN104) is available here. See all funded NeuroNEXT studies here.

March 28, 2014

Follow-up to CAPTION Study funded by National Heart, Lung, and Blood Institute

The National Heart, Lung, and Blood Institute (NHLBI) within the National Institutes of Health, has funded a follow-up study to CAPTION, titled "MEDication Focused Outpatient Care for Underutilization of Secondary Prevention." This project is a multi-center, cluster-randomized study utilizing a centralized cardiovascular risk service (CVRS) to determine the extend to which the CVRS model managed by clinical pharmacists will be implemented, and to what extent that improves adherence to cardiovascular disease (CVD) guidelines using the Guideline Advantage metrics.

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